It's the 12th matchup between No. 8 seed Anderson and No. 9 Isner, who leads the head-to-head 8-3.
Steve Tignor previews the men's semifinals at Wimbledon. "I think Rafa, in the end deserves to win once again". Isner also won their only meeting on grass, at Queen's Club in 2008. Just feel sorry for him and congrats to Kevin.
Isner had never got past the third round at Wimbledon before this year while a run to the last-eight at the 2011 US Open had been his previous best at the majors.
Kevin Anderson celebrates beating Roger Federer on Wednesday. It doesn't get much bigger than that, which means the question now becomes: Will such a titanic victory build Anderson's confidence, or will it lead to a letdown, as it has for so many others who have knocked off Federer at the Slams over the years?
In a match that delivered quality throughout, Nadal recovered from two sets to one down to treat the Wimbledon crowd to a match few will forget. Djokovic has the slight edge at overall Tour-level at 26-25, but Nadal ended a seven-match losing streak against the Serb at Madrid previous year and also won their only meeting so far in 2018 in the semi-finals of the Rome Masters.
Next up for the Spaniard is a blockbuster last four showdown with Novak Djokovic.
"There is no one other match in the history of tennis that has been played more than our match".
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When they scored, it was 50/50 game. "I'm proud to make ex-players proud and I'm sure it's bringing back memories for them". There's a lot we could have done better.
While Nadal and Djokovic are old hands at winning Slams, the man stood on the opposite side of the net in Sunday's final will be bidding to win a first major. But Rafa has won the last two in straight sets.
As it was, Del Potro came out on top in both counts by conjuring 77 of those winners and blasting down 33 aces - and still came off second best.
"With how I'm feeling physically and mentally, I'm in a very good spot".
Federer suffers shock Wimbledon quarter-final loss to Anderson The two-time Wimbledon champion will face Djokovic, a three-time victor at the All England Club, for a place in Sunday's final.
"I don't know what to say right now".
But Nadal was first to break in the deciding set and he built a 5-3 advantage with a looped forehand victor before confirming his final four place with a volley after four hours and 48 minutes.
Del Potro was in danger of being dragged into a fifth set when he squandered four match points, one with a double-fault, at 5-4 having hit back from 1-3 down.