While his technical acumen is on par with the best in the business, the English Premier League is altogether a different proposition for any manager.
Sead Kolasinac suffered a knee ligament injury against Chelsea in pre-season, while Nacho Monreal only returned to full training this week. Even without key players the intensity and organisation of Guardiola's men could not be matched by Arsenal, just as it couldn't by Chelsea in last week's Community Shield. Expect goals at the Emirates Stadium as a new dawn settles on the London Horizon.
The match can be viewed on Sky Sports Premier League in the UK.
Sterling was allowed to cut in from the left and slot home while Silva roamed in the box before tucking home Benjamin Mendy's cross.
Aguero saw an early second-half strike deflected behind for a corner before Emery brought on Alexandre Lacazette for Aaron Ramsey.
The new Arsenal Spanish boss though believes City will have the upper hand as they have a consistent style due to manager Pep Guardiola being with them for two years and he is still bedding himself in at the Gunners.
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Facing something of an injury crisis at left-back, Emery has been forced to mix things up ahead of his first season in the Premier League.
For Emery, the first question on his mind is whether he picks Petr Cech in goal or Bernd Leno.
Wenger's remarkable feats in the first half of his reign will stand the test of time, but few Arsenal supporters lamented his departure after 14 years without a league title.
Midfielders Kevin De Bruyne and Raheem Sterling are back in contention for City.
Instead, Guardiola has opted to start Bernardo Silva in central midfield, while Riyad Mahrez makes his debut for City on the right flank. "I'm not rigid to stick to one formation or way of playing". If Arsenal play a defensively tight game, then they have the individual quality in them to stop Manchester City from winning, but based on merit, City will take the win at the Emirates. His clinical nayure and proper positioning will make him a threat for City, and he indeed is the one player to watch out for when the two sides meet.