The US president said in a tweet that McGahn would depart in the autumn, by which time the administration hopes to have installed Brett Kavanaugh on the supreme court.
While the Times presented McGahn's cooperation as "unusual", Trump tweeted that it was all a part of the unprecedented level of transparency his administration has had with regards to the Russian Federation investigation.
McGahn is widely seen inside the White House as a force for reason when it comes to the administration's response to the Mueller investigation.
As members of Trump's legal team looked into potential conflicts of interest involving Mueller, Trump directed McGahn to call Deputy Attorney General Rod Rosenstein to raise the perceived conflicts and push for Mueller's ouster, a person familiar with the matter said at the time. Other Trump advisors have suggested aggressive response to Mueller's probe, but McGahn has quietly advocated for stasis. Nothing to see here, though, according to a top spokesman for the Iowa Republican.
McGahn threatened to resign previous year if Trump removed special counsel Robert Mueller from the Russian election meddling investigation.
Mr McGahn's departure was widely expected.
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The White House counsel, Don McGahn, may leave the Trump administration in short order after cooperating extensively with the special counsel's investigation into possible criminal wrongdoing from President Donald Trump.
Grassley reacted to the announcement with his own tweet, expressing concern with the coming departure of an attorney who has urged the president to fully cooperate with Special Counsel Robert S. Mueller's Russian Federation election meddling probe.
"People like him", Ms Sanders said of Mr Flood.
George Hartmann, spokesman for the committee, said Grassley viewed McGahn as the lynchpin to Trump's push to fill judicial vacancies. According to The New York Times, McGahn met with investigators for a total of 30 hours over the past nine months.
In recent months, as he has worked on the Kavanaugh confirmation, McGahn's challenges have only mounted.