"Just in the last 36 hours the air force attacked Iranian warehouses containing Iranian weapons in the Damascus worldwide airport", Netanyahu said at the start of a cabinet meeting, according to his office.
On Friday, Syrian state news agency SANA reported that the country's air defenses intercepted missiles fired at the Damascus global airport at around 11:00 p.m. local time, with a military source attributing the attack to Israel.
Another official told SANA traffic at the airport had not been disrupted.
Shortly after 11PM, Syrian media began reporting that explosions were being heard throughout Damascus, along with simultaneous reports from Lebanon claiming there was an abundance of Israeli fighter jets operating in the region.
The Syrian Observatory for Human Rights confirmed the warehouse was hit, and said a second target south of Damasscus was also struck.
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"The results of the assault were limited to the targeting of a warehouse at Damascus International Airport", the source added. However, the Arab country's air defense systems have thwarted most of the attacks.
Israel is able to continue to get away with attacks against Syria only because it is protected by the United States, the Syrian Foreign Ministry said following the IAF's latest attack on its soil.
Syrian state media broadcast footage of what it said were the air defences firing, with bright lights seen shooting across the night sky.
Israeli Prime Minister Benjamin Netanyahu has vowed not to let Tehran - a supporter of President Assad - entrench itself militarily in the war-torn country.
Russian Federation is a main ally of Damascus.