(Like the London patient, the Düsseldorf patient's identity has been concealed for privacy.) Post-bone marrow transplant, the Düsseldorf patient's gut and lymph node biopsies revealed no infectious HIV after three months off of an antiviral drug regimen.
The so-called "Düsseldorf patient" case was announced Wednesday, at the Conference on Retroviruses and Opportunistic Infections in Seattle, New Scientist reported.
A man identified only as the "London patient" has become the second person ever to be declared cured of HIV.
Publishing in the science journal "Nature", researchers from University College London detail how they have achieved HIV remission in a man known publicly as the London Patient, making this the second of only two documented prolonged cases of remission of this kind in the world. It made him resistant to HIV, just like the first cured case of Timothy Ray Brown, better known as the "Berlin patient", a decade ago. But there's an ever-present danger of raising false hopes for millions of people living with HIV, because the stem cell transplant is neither practical nor safe enough to use on anyone who has just HIV and not an otherwise fatal cancer. But the cost of these treatments, side effects, and rise of viral resistance to the therapy, mean that a cure capable of ridding patients of the infection still remains a major medical priority.
For the third time in history, a person living with HIV is reportedly free of the virus after undergoing a bone marrow transplant, reports the New Scientist. Doctors suggested a stem cell transplant to cure the cancer. As part of his treatment for leukemia, which is a cancer of the immune system, his immune cells were destroyed and replaced with donor cells with the mutation.
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We need to increase everything if we want to arrive as one of the best clubs in Europe. We dominated the game but could not kill it off.
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Once again, however, they did not panic and pushed any pressure their toils might have caused back in the direction of Merseyside. Having claimed the first goal, Raheem Sterling only took another 13 minutes to complete his hat-trick and the contest was over.
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"We haven't cured HIV, but (this) gives us hope that it's going to be feasible one day to eliminate the virus", she said. A small amount of people who are resistant to HIV have two mutated copies of this receptor; meaning the virus can't penetrate the cells it would normally infect. Pills taken daily can keep HIV levels so low the virus is not transmittable to sex partners, but not everyone takes them as prescribed. Some viruses have exhibited the natural ability to develop drug-resistance and people not taking antiretrovirals properly can help speed up that process and pass drug-resistant strains to others. Though their procedures were different from those the London Patient and the Berlin Patient, this demonstrates that caution is critical when we talk about this as a "cure".
These events mark an important milestone in securing domestic sustainable financing for the HIV response in Vietnam and ensuring that people living with HIV access treatment services.
With three patients becoming HIV-free after undergoing the same type of transplant, this is no longer a coincidence and the word cure flows nearly naturally - but this is by no means a scalable treatment. After receiving treatment, both patients were eventually taken off their anti-retroviral medications and subsequent examination showed that that even with very sensitive blood tests, the team could not detect HIV in their blood.
Most importantly, the HIV community learned that Brown's case was not unique.